Brain's Default Mode Network
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The maturing architecture of the brain's default network.
In recent years, the brain's "default network," a set of regions characterized by decreased neural activity during goal-oriented tasks, has generated a significant amount of interest, as well as controversy. Much of the discussion has focused on the relationship of these regions to a "default mode" of brain function. In early studies, investigators suggested that, the brain's default mode suppo...
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Fig.1: t-score maps showing resting state correlations with PCC/preCun (p<0.05). Right column: significant differences between patients and controls. Tab.1: Brain regions correlating significantly (p<0.05) with PC/preCun in controls. Negative t-scores indicate anticorrelation. Tab.2: Brain regions correlating significantly (p<0.05) with PC/preCun in patients. Negative tscores indicate anti-corr...
متن کاملMultimodal Imaging of Alzheimer Pathophysiology in the Brain's Default Mode Network
The spatial correlations between the brain's default mode network (DMN) and the brain regions known to develop pathophysiology in Alzheimer's disease (AD) have recently attracted much attention. In this paper, we compare results of different functional and structural imaging modalities, including MRI and PET, and highlight different patterns of anomalies observed within the DMN. Multitracer PET...
متن کاملMapping the self in the brain's default mode network
The brain's default mode network (DMN) has become closely associated with self-referential mental activity, particularly in the resting-state. While the DMN is important for such processes, it has functions other than self-reference, and self-referential processes are supported by regions outside of the DMN. In our study of 88 participants, we examined self-referential and resting-state process...
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44 SCIENTIFIC AMERICAN' Imagine you are almost dozing in a lounge chair outside, with a magazine on your lap. Suddenly, a fly lands on your arm. You grab the magazine and swat at the insect. What was going on in your brain after the fly landed? And what was going on just before? Many neuroscientists have long assumed that much of the neural activity inside your head when at rest matches your su...
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تاریخ انتشار 2016